Peer-reviewed veterinary case report
Hypertriglyceridemia links endocrine diseases to pancreatitis in dogs
By Kim, Hakhyun et al.·Published in Journal of the American Animal Hospital Association·2019·College of Veterinary Medicine (H.K., South Korea·View original on PubMed →
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Original publication title: Evaluation of Hypertriglyceridemia as a Mediator Between Endocrine Diseases and Pancreatitis in Dogs.
- Species:
- dog
Plain-English summary
A group of dogs diagnosed with pancreatitis was found to have a higher likelihood of also having diabetes or Cushing's disease (hyperadrenocorticism). Specifically, dogs with diabetes were 12 times more likely to develop pancreatitis compared to those without it. The study suggests that high triglyceride levels (hypertriglyceridemia) may play a role in the connection between diabetes and pancreatitis, but not with Cushing's disease. More research is needed to fully understand these links and how they affect treatment options for affected dogs.
People also search for: dog pancreatitis symptoms · diabetes in dogs treatment · Cushing's disease and pancreatitis in dogs
Abstract
The role of hypertriglyceridemia (HTG) secondary to endocrine diseases in the occurrence of pancreatitis in dogs has not been fully investigated. The objective of the present study was to evaluate HTG as a mediator between endocrine diseases and pancreatitis in dogs. The study design was a retrospective case-control study. Medical records of dogs newly diagnosed with acutely presenting pancreatitis between 2012 and 2014 were reviewed for the presence or absence of hyperadrenocorticism (HAC), diabetes mellitus (DM), and hypothyroidism. A matched case-control analysis was performed, and the association between endocrine diseases and pancreatitis was evaluated using multiple logistic regression analysis. In dogs with pancreatitis, the odds of HAC (P < .001) and DM (P < .001) were 4.5 and 12.4 times that of dogs without pancreatitis, respectively. HTG significantly mediated the association between DM and pancreatitis but not between HAC and pancreatitis. Additional studies will be necessary to confirm these findings and to further elucidate the associations between endocrine diseases and pancreatitis.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/30776262/