Peer-reviewed veterinary case report
IGF-1 hormone levels in cats with temporary and permanent diabetes
By Alt, N et al.·Published in Research in veterinary science·2007·Clinic of Small Animal Internal Medicine·View original on PubMed →
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Original publication title: Evaluation of IGF-1 levels in cats with transient and permanent diabetes mellitus.
- Species:
- cat
Plain-English summary
A group of diabetic cats was studied to see if their IGF-1 levels (a hormone related to insulin) could help determine if they would go into remission or need ongoing treatment. Out of 32 cats, 13 went into remission within 16 weeks of starting insulin therapy, while 19 continued needing insulin. The researchers found that IGF-1 levels were lower in both groups compared to healthy cats before treatment, but both groups showed an increase after starting insulin. Interestingly, IGF-1 levels normalized faster in cats that went into remission, but measuring these levels didn't help predict which cats would need long-term treatment.
People also search for: cat diabetes treatment · insulin therapy for diabetic cats · IGF-1 levels in cats
Abstract
It was investigated if IGF-1 levels in cats which experience diabetic remission (i.e. transient diabetes mellitus) differ from those in cats with permanent disease. Thirteen of 32 diabetic cats showed remission within 16 weeks after initiating insulin therapy, 19 cats continued to need insulin therapy. IGF-1 concentrations were measured before (t(0)), 1-3 (t(1)) and 4-8 (t(2)) weeks after initiating insulin therapy. No difference in IGF-1 levels was found between cats with transient and permanent diabetes at any point in time. In both groups of cats IGF-1 concentrations were significantly lower compared to those of controls before insulin administration. After starting insulin therapy IGF-1 increased significantly in both groups. In cats with transient diabetes IGF-1 levels were not different from controls already at t(1), whereas in cats with permanent diabetes it took until t(2). Although IGF-1 levels seem to normalize faster in cats with transient diabetes mellitus, measurement is not helpful to predict the course of the disease.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17367830/