Peer-reviewed veterinary case report
Magnesium levels in hyperthyroid cats compared to healthy cats
By Gilroy, Cornelia V et al.·Published in Canadian journal of veterinary research = Revue canadienne de recherche veterinaire·2006·Department of Pathology and Microbiology·View original on PubMed →
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Original publication title: Evaluation of ionized and total serum magnesium concentrations in hyperthyroid cats.
- Species:
- cat
Plain-English summary
A group of hyperthyroid cats was tested for magnesium levels in their blood to see if their condition affected these levels. The study found that while the total magnesium levels were similar to healthy cats, the ratio of ionized (active) magnesium was lower in those with higher thyroid hormone levels. This suggests that severe hyperthyroidism might lead to lower active magnesium levels. The cats with hyperthyroidism also had lower total protein levels compared to healthy cats.
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Abstract
Hyperthyroidism can increase the renal excretion of magnesium and thus cause hypomagnesemia in various species. Anaerobically collected blood samples from 15 hyperthyroid and 40 normal, healthy cats were analyzed with an ion-selective electrode analyzer and a serum biochemical analyzer. There was no significant difference in ionized or total serum magnesium concentration between the 2 groups, but there was a significant difference (P = 0.004) in the ratio of ionized to total serum magnesium concentrations between the healthy cats and the hyperthyroid cats with thyroxine (T4) concentrations at or above the median. There was a significant correlation (r = 0.894, P = 0.000) between the ionized and total magnesium concentrations in the hyperthyroid cats. The hyperthyroid cats had a significantly lower (P = 0.003) total serum protein concentration than the healthy cats. A significant negative correlation (r = -0.670, P = 0.006) was detected between the ionized magnesium and logarithmically transformed total T4 concentrations in the hyperthyroid cats, which suggests that the severity of hyperthyroidism may contribute to a decrease in the ionized magnesium concentration.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16639946/