Peer-reviewed veterinary case report
Iron deficiency signs in dogs donating blood six times a year
By Foy, D S et al.·Published in Journal of veterinary internal medicine·2015·Department of Medical Sciences·View original on PubMed →
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Original publication title: Evaluation of Iron Deficiency Using Reticulocyte Indices in Dogs Enrolled in a Blood Donor Program.
- Species:
- dog
Plain-English summary
A group of dogs that donated blood six or more times in a year showed signs of iron deficiency. Researchers compared these donor dogs to healthy dogs and found that the donor dogs had lower levels of certain blood components that indicate iron status. While the overall iron levels were similar between the two groups, the donor dogs had a higher risk of developing issues related to low iron. This suggests that regular blood donation could lead to iron deficiency in dogs, so it's important for owners of frequent donor dogs to monitor their pet's health and discuss any concerns with their veterinarian.
People also search for: dog blood donation iron deficiency · signs of low iron in dogs · how often can dogs donate blood
Abstract
BACKGROUND: People donating blood more than twice annually are at risk of developing iron deficiency. Little is known about the iron status of dogs enrolled in blood donor programs. HYPOTHESIS: Dogs donating blood ≥6 times annually will show evidence of iron deficiency based on their reticulocyte indices. ANIMALS: Thirteen dogs enrolled in a blood donor program donating ≥6 times over the preceding 12 months and 20 healthy nondonor control dogs. METHODS: Prospective observational study. Mature red blood cell (RBC) indices, reticulocyte indices, serum iron, serum ferritin, and total iron-binding capacity (TIBC) were compared between groups. RESULTS: Packed cell volume (median 47%, range 40-52%, P < .01), hematocrit (median 46.4%, range 40.3-52.5%, P < .01), and reticulocyte count (median 16,000/μL, range 9,000-38,000/μL, P < .01) were significantly lower in the blood donor dogs. No statistically significant differences were noted in the mature RBC indices between groups. Both reticulocyte mean corpuscular volume (median 88.8 fL, range 83.4-95.5 fL, P = .03) and reticulocyte hemoglobin content (median 24.6 pg, range 23.1-26.6 pg, P < .01) were significantly lower in the blood donor group. Serum iron and ferritin were similar between groups; however, TIBC was significantly higher in the control group (median 403 μg/dL, range 225-493 μg/dL, P = .02). CONCLUSIONS: The findings in dogs donating ≥6 times annually suggest the presence of iron-deficient erythropoiesis in this population.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/26340143/