Peer-reviewed veterinary case report
Long-term results of collagen injections for female dog urinary leaks
By Barth, Andrea et al.·Published in Journal of the American Veterinary Medical Association·2005·Department of Small Animals·View original on PubMed →
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Original publication title: Evaluation of long-term effects of endoscopic injection of collagen into the urethral submucosa for treatment of urethral sphincter incompetence in female dogs: 40 cases (1993-2000).
- Species:
- dog
Plain-English summary
A group of 40 female dogs with urinary incontinence due to urethral sphincter incompetence received collagen injections to help them regain control over their bladder. After the treatment, about 68% of the dogs remained continent for an average of 17 months, while others showed improvement with additional medication. Some dogs experienced a return of incontinence after a year, likely due to changes in the collagen deposits. Overall, the treatment was considered successful, with only mild side effects reported in a few cases.
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Abstract
OBJECTIVE: To evaluate long-term success of endoscopic injection of collagen into the urethral submucosa in female dogs with urinary incontinence caused by urethral sphincter incompetence. DESIGN: Retrospective study. ANIMALS: 40 incontinent female dogs. PROCEDURE: Medical records were reviewed for outcome and other results for dogs in which a cystoscope was passed into the urethra for deposition of 3 collagen deposits into the submucosa. RESULTS: 27 (68%) dogs were continent for 1 to 64 months (mean, 17 months) after the collagen injection. In another 10 dogs, incontinence improved and in 6 of these dogs, full continence was regained with administration of additional medication. In 3 dogs, incontinence was unchanged. As long as 12 months after injection, there was a deterioration in the initial result in 16 dogs, after which their condition stabilized. Mild and transient adverse effects developed in 6 (15%) dogs. CONCLUSIONS AND CLINICAL RELEVANCE: Long-term success of endoscopic injection of collagen was satisfactory. Relapse of incontinence might be caused by flattening of the collagen deposits rather than resorption of the collagen.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15646576/