Peer-reviewed veterinary case report
Using surgical glue for mesh fixation in laparoscopic hernia repair
By Liu J et al.·2026·Department of Hernia and Abdominal Wall Surgery, China·View original on Europe PMC →
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Original publication title: Evaluation of NBCA(n-butyl-2-cyanoacrylate) surgical glue for mesh fixation in laparoscopic treatment of primary lateral incisional hernias.
Plain-English summary
This study looked at a new type of surgical glue called NBCA (n-butyl-2-cyanoacrylate) to see if it could be a better option than traditional tacks for fixing mesh during laparoscopic surgery for lateral incisional hernias. Researchers compared two groups of patients: one group had the glue used along with tacks, while the other group had tacks only. They found that patients who had the glue reported less pain after surgery and were able to return to their normal activities faster, although the overall complication rates were similar between both groups. The glue did not increase the chances of the hernia coming back or cause more problems, suggesting it could be a safe alternative, especially in delicate areas. Overall, the treatment with the glue showed some benefits, but more studies are needed to confirm its long-term safety and effectiveness.
Abstract
<h4>Purpose</h4>Traditional mesh fixation using tacks in laparoscopic repair of lateral incisional hernias (IHs) carries risks near sensitive anatomical areas. This retrospective cohort study evaluates the efficacy and safety of NBCA (n-butyl-2-cyanoacrylate) surgical glue as an alternative to tacks for mesh fixation.<h4>Methods</h4>Patients with primary lateral primary incisional hernias who were treated by laparoscopic technique in Department of Hernia and Abdominal Wall Surgery in Beijing Chaoyang Hospital from Jan 2017 to Dec 2023 were recruited in our study. Patients were divided into two groups: surgical glue with tacks group (GT, n=72) and tacks only group (TO, n=72). Demographics, operative details, hematoma, seroma, chronic pain, recurrence and other complications were retrospectively compared between the two groups.<h4>Results</h4>A total of 144 patients were recruited in our study. According to different fixation, there were 72 patients in GT group and 72 in TO group. Compared to TO group, the GT group had a significantly lower postoperative pain score at 24 hours, 72 hours and 120 hours(4.0vs.3.0, 3.0vs.2.0, 2.0vs.1.0, respectively, P<0.001). The recurrence was similar between the two group(2.7%vs.2.7%, respectively, P>0.05). GT group had a quicker time to return to normal activities(7vs.11days, respectively, P<0.001). The overall complication rates were equivalent between the two groups (9.7% vs.19.4%, respectively, P>0.05).<h4>Conclusion</h4>NBCA surgical glue may provide certain clinical advantages in laparoscopic lateral IH repair, including reduced postoperative pain and faster recovery, although the magnitude of pain reduction is modest. Glue-assisted fixation appears safe and does not increase recurrence or complication rates. Its use may be particularly beneficial in anatomically sensitive regions where traditional fixation poses higher risks. Further prospective multicenter studies are needed to confirm its long-term safety and effectiveness.
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Search related cases →Original publication on Europe PMC: https://europepmc.org/article/MED/41493604