Peer-reviewed veterinary case report
Oxidative stress and antioxidant treatment in dogs with bloody
By M. R. Krishna Nath et al.·Published in Journal of Veterinary and Animal Sciences·2023·MVSc. scholar, Department of Veterinary Clinical Medicine, Ethics and Jurisprudence, College of Veterinary and Animal Sciences, Mannuthy, Thrissur- 680651, Kerala Veterinary and Animal Sciences University, Kerala, India., IN·View original on DOAJ →
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Original publication title: Evaluation of oxidative stress and efficacy of antioxidant therapy in dogs with haemorrhagic gastroenteritis
- Species:
- dog
Plain-English summary
Fifteen dogs with vomiting and diarrhea were diagnosed with hemorrhagic gastroenteritis (HGE), a serious condition that can cause severe dehydration. Tests showed these dogs had higher levels of oxidative stress, indicating damage to their cells. To help, veterinarians treated them with an antioxidant supplement called N-acetyl cysteine for five days. This treatment effectively reduced oxidative damage, helping the dogs recover from their symptoms and improving their overall health.
People also search for: dog vomiting diarrhea treatment · hemorrhagic gastroenteritis in dogs · N-acetyl cysteine for dogs
Abstract
The present study was conducted to evaluate the alterations in oxidative stress parameters in dogs suffering from haemorrhagic gastroenteritis (HGE). Dogs presented with vomiting and diarrhoea were screened and fifteen animals with signs suggestive of HGE were included in the study. The oxidative stress parameters, serummalondialdehyde (MDA) level, total antioxidant status (TAS) and plasma glutathione peroxidase (GSH-Px) activity were studied. The values were compared with the values from six apparently healthy dogs. A significant increase was noticed in the mean values of serum MDA and TAS of diseased animals at the time of presentation when compared to healthy animals whereas the activity of plasma GSH-Px was found to be lower than in healthy dogs. Supplementation with N-acetyl cysteine @ 70 mg/kg or five days was found effective in managing the oxidative injury in the affected animals.
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Search related cases →Original publication on DOAJ: https://doi.org/10.51966/jvas.2023.54.1.86-90