Peer-reviewed veterinary case report
Normal blood test levels for heart health in healthy Saluki dogs
By Brennan, Christopher et al.·Published in PloS one·2022·Department of Small Animal Clinical Sciences, United States·View original on PubMed →
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Original publication title: Evaluation of plasma N-terminal pro-B-type natriuretic peptide levels in healthy North American Salukis with normal echocardiographic measurements.
- Species:
- dog
Plain-English summary
A group of 33 healthy Salukis had their heart health checked using echocardiograms and blood tests to measure a substance called NT-proBNP, which helps assess heart function. The study found that the NT-proBNP levels in these dogs were within the normal range established for all breeds, meaning the current reference values are suitable for evaluating heart health in Salukis. This information can help veterinarians determine if a Saluki has heart problems based on NT-proBNP levels.
People also search for: Saluki heart health test · NT-proBNP levels in dogs · healthy Saluki heart function
Abstract
Measurement of N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels has been shown to have clinical significance for diagnosis and management of heart disease in dogs. Evaluation of current reference limits for specific breeds is necessary to ensure the test can accurately distinguish between healthy and diseased animals. The objective of this study is to evaluate the adequacy of currently established NT-proBNP reference limits for clinical use in healthy Salukis. Cardiac health of 33 clinically healthy Salukis was evaluated via echocardiography using available breed standards. Plasma concentrations of NT-proBNP were measured using a commercially available assay. A one-sided 97.5% upper reference limit for the NT-proBNP concentrations was calculated using non-parametric percentile method. The 97.5% upper reference limit was 769 pmol/L (90% CI, 547-1214 pmol/L) for the study dogs. This upper reference limit was within the currently established non-breed specific NT-proBNP upper reference limit of 900 pmol/L. No relationship between sex, age, or body weight on plasma levels of NT-proBNP was noted. Results of this study supports the use of currently available non-breed specific NT-proBNP cut-off values for clinical evaluation of healthy Salukis.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/35100273/