Peer-reviewed veterinary case report
Pradofloxacin treatment for cat nasal infections and rhinitis
By Spindel, Miranda E et al.·Published in Journal of feline medicine and surgery·2008·Department of Clinical Sciences, United States·View original on PubMed →
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Original publication title: Evaluation of pradofloxacin for the treatment of feline rhinitis.
- Species:
- cat
Plain-English summary
A group of 40 cats with suspected bacterial upper respiratory infections (URIs) were treated with either amoxicillin or pradofloxacin to see which worked better for their nasal congestion and discharge. The most common germs found in these cats included feline herpesvirus and Mycoplasma species. While both medications helped, pradofloxacin showed slightly better results, with 85% to 92% of cats responding well to the treatment. Importantly, no serious side effects were noted, suggesting that pradofloxacin is a safe option for cats suffering from these infections.
People also search for: cat nasal discharge treatment · feline upper respiratory infection antibiotics · pradofloxacin for cats
Abstract
Forty humane society cats with suspected bacterial upper respiratory infections (URIs) were studied in order to compare amoxycillin and pradofloxacin for treatment of rhinitis and describe common pathogens. Nasal discharges were collected prior to random placement into one of three treatment groups. Cats failing to initially respond were crossed to the alternate drug. Drug toxicity was not noted. The organisms most frequently isolated or amplified pre-treatment were feline herpesvirus-1 (75%), Mycoplasma species (62.5%), Bordetella species (47.5%), Staphylococcus species (12.5%) and Streptococcus species (10.0%). No differences in clinical scores between groups over time were noted. Overall response rates for amoxycillin at 22 mg/kg, q12 h for seven doses (10/15 cats; 67%), pradofloxacin at 5mg/kg, q24 h for seven doses (11/13 cats; 85%), and pradofloxacin at 10mg/kg, q24 h for seven doses (11/12 cats; 92%) were not statistically significant. Results suggest that pradofloxacin can be a safe, efficacious therapy for some cats with suspected bacterial URI.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18619887/