Peer-reviewed veterinary case report
Inhaled nitric oxide lowers lung pressure in Maltese dog with heart
By Hirakawa, A et al.·Published in The Journal of veterinary medical science·1996·Department of Veterinary Medicine, Japan·View original on PubMed →
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Original publication title: Evaluation of pulmonary vasodilatory capacity with inhaled nitric oxide in a dog with patent ductus arteriosus.
- Species:
- dog
Plain-English summary
A female Maltese dog with a heart condition called patent ductus arteriosus (PDA) was experiencing heart failure and high blood pressure in her lungs. During a procedure to assess her heart, the vet tested inhaled nitric oxide to see if it could help lower the pressure in her lungs. The nitric oxide worked quickly to reduce the lung pressure without affecting her overall blood flow. This suggests that inhaled nitric oxide could be a safe and effective treatment option for dogs with similar heart issues.
People also search for: Maltese dog heart failure treatment · patent ductus arteriosus in dogs · inhaled nitric oxide for dogs
Abstract
A female Maltese dog with patent ductus arteriosus (PDA) showing left congestive heart failure and moderate pulmonary hypertension was evaluated for pulmonary vasodilatory capacity using low concentrations of inhaled nitric oxide (NO) in comparison with oxygen during preoperative cardiac catheterization. Increasing the inspired oxygen concentration (FiO2) to 1.0 without adding NO did not reduce the mean pulmonary arterial pressure (mPAP). However, inhalation of NO at FiO2 1.0 reduced mPAP rapidly without changing other hemodynamic and gas exchange parameters. From these results, inhaled NO caused selective pulmonary vasodilation without producing systemic vasodilation, which may provide a safe and effective mean of evaluating the pulmonary vasodilatory capacity of dogs with PDA.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/8844606/