Peer-reviewed veterinary case report
Safety and immune response of reduced volume cat vaccines
By Jas, Dominique et al.·Published in Vaccine·2021·Boehringer-Ingelheim Animal Health SCS France, France·View original on PubMed →
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Original publication title: Evaluation of safety and immunogenicity of feline vaccines with reduced volume.
- Species:
- cat
Plain-English summary
A study tested a new smaller vaccine (0.5 ml) for cats against common viruses like feline herpesvirus and feline leukemia, comparing it to the standard 1 ml vaccine. The smaller vaccine was found to be safe and well-tolerated, causing fewer side effects while still providing the same level of protection. This means that cat owners can expect a more convenient vaccination experience without sacrificing their pet's immunity.
People also search for: cat vaccine side effects · feline leukemia vaccine safety · small cat vaccine dosage
Abstract
A non adjuvanted vaccine against feline herpesvirus, feline calicivirus, feline panleucopenia and feline leukemia has been formulated in reduced volume (0.5 ml) with the same antigen content as the conventional 1 ml presentation. This paper reports studies evaluating the safety and the immunogenicity of this reduced volume vaccine in comparison with the conventional volume vaccine. The safety of both vaccines was evaluated in a small sized laboratory trial. It was further tested in a randomized controlled field trial on a total of 398 cats. Immediate and delayed local and systemic adverse events were monitored after vaccination. The immunogenicity of each vaccine was also checked by serological antibody responses against the vaccines antigens during the laboratory trial. These studies showed that the 0.5 ml vaccine was well tolerated in cats, inducing less local events, while keeping the same immunogenicity as the corresponding 1 ml vaccine. Reducing the volume of the vaccine is a way to improve the convenience of administration and to help following vaccination guidelines with the aim of reducing the incidence of adverse events following vaccination.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/33485645/