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Peer-reviewed veterinary case report

Food allergy testing in dogs with corn and soy sensitivity

By Jackson, H A et al.·Published in Veterinary dermatology·2003·Department of Clinical Sciences, United States·View original on PubMed

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Original publication title: Evaluation of the clinical and allergen specific serum immunoglobulin E responses to oral challenge with cornstarch, corn, soy and a soy hydrolysate diet in dogs with spontaneous food allergy.

Species:
dog

Plain-English summary

A group of 14 dogs with known allergies to soy and corn were put on a special duck and rice diet to help reduce their itching and skin problems. After about 78 days, they were given small amounts of cornstarch, corn, and soy to see if their symptoms would return. The dogs showed significant itching after eating cornstarch, corn, and soy, but not after eating a diet made with hydrolyzed soy protein. Overall, the dogs improved on the special diet, and the skin tests showed less sensitivity to soy and corn after the diet change.

People also search for: dog food allergy symptoms · dog itching corn allergy · hydrolyzed soy diet for dogs

Abstract

Fourteen dogs with known clinical hypersensitivity to soy and corn were maintained on a limited antigen duck and rice diet until cutaneous manifestations of pruritus were minimal (78 days). Sequential oral challenges with cornstarch, corn and soy were then performed. Subsequently, the dogs were fed a diet containing hydrolysed soy protein and cornstarch. Throughout the study period the dogs were examined for cutaneous manifestations of pruritus and, additionally, serum was collected for measurement of allergen-specific and total immunoglobulin (Ig)E concentrations. Intradermal testing with food antigens was performed prior to entry into the study and after 83 days. A statistically significant clinical improvement was measured between days 0 and 83. Significant pruritus was induced after oral challenge with cornstarch, corn and soy (P = 0.04, 0.002, 0.01, respectively) but not with the hydrolysed diet (P = 0.5). The positive predictive value of the skin test for soy and corn allergy was reduced after feeding a soy and corn free diet. Although increases in soy and corn-specific serum IgE concentrations were measured in individual dogs post challenge they were not statistically significant and could not be used to predict clinical hypersensitivity.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/12895222/