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Peer-reviewed veterinary case report

Pradofloxacin tablets for treating dog skin infections

By Restrepo, Christina et al.Ā·Published in Journal of the American Animal Hospital AssociationĀ·2010Ā·School of Veterinary Medicine, United StatesĀ·View original on PubMed →

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Original publication title: Evaluation of the clinical efficacy of pradofloxacin tablets for the treatment of canine pyoderma.

Species:
dog
Skin & coatDogs

Plain-English summary

Twenty dogs with skin infections called pyoderma were treated with a new antibiotic called pradofloxacin. The dogs were given the medication daily for several weeks, and their skin was examined to monitor improvement. After 3 to 6 weeks, all the dogs showed good to excellent improvement in their skin condition. This suggests that pradofloxacin is effective for treating both superficial and deep pyoderma in dogs.

People also search for: dog skin infection treatment Ā· pradofloxacin for dogs Ā· pyoderma in dogs symptoms

Abstract

A third-generation fluoroquinolone, pradofloxacin (PRA), is currently being developed to treat bacterial infections in dogs. The purpose of this study was to assess the clinical efficacy in 20 dogs affected with superficial and deep pyoderma. An initial aerobic skin culture was performed in dogs with superficial pyoderma; aerobic/anaerobic tissue culture was performed in dogs with deep pyoderma; and skin cytology and biopsies were obtained from all dogs. Pradofloxacin (approximately 3 mg/kg per os [PO]) was administered daily to all dogs. Clinical efficacy was recorded at 4 weeks for dogs with superficial pyoderma and at 3 and 6 weeks for dogs with deep pyoderma. At a mean dosage of 3.7 mg/kg PO once daily, PRA treatment resulted in an excellent to good clinical response within 3 to 6 weeks for all 20 dogs with superficial and deep pyoderma.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/20810550/