Peer-reviewed veterinary case report
Using tepoxalin and meloxicam for cats - effects and safety
By Charlton, Anna N et al.·Published in Journal of Feline Medicine and Surgery·2013·Comparative Pain Research Laboratory, College of Veterinary Medicine, North Carolina State University, Raleigh, NC, USA, United States·View original on Crossref →
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Original publication title: Evaluation of the clinical use of tepoxalin and meloxicam in cats
- Species:
- cat
Plain-English summary
A review of medical records showed that cats treated with either tepoxalin or meloxicam, two common pain medications, generally tolerated these drugs well. Tepoxalin was given for an average of 11 days, while meloxicam was prescribed for about 93 days. Some cats experienced mild side effects, but most blood tests remained normal after treatment. Overall, both medications were effective for managing pain in cats without causing serious issues.
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Abstract
Medical records where tepoxalin (Zubrin) or meloxicam (Metacam) were prescribed in cats were reviewed and data extracted. Comparisons were performed for exploring changes between pre- and post-non-steroidal anti-inflammatory drug course laboratory tests. Seventy-nine medical records fit the inclusion criteria (n = 57 and n = 22, tepoxalin and meloxicam, respectively). The median dosages administered were 13 and 0.029 mg/kg / day (tepoxalin and meloxicam, respectively). Median prescription durations were 11 (2–919) and 93 (4–1814) days for tepoxalin and meloxicam, respectively. Suspected adverse events were reported for tepoxalin (9%, 5/57 cats) and meloxicam (18%, 4/22 cats) a median of 774 and 448 days, respectively, after the prescription started. For cats prescribed meloxicam, there were several statistically significant changes for serum biochemistry and hematology parameters, but median values were within normal limits. These valuable clinical data suggest that tepoxalin and meloxicam are well tolerated in the clinical setting at the doses prescribed in this study.
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Search related cases →Original publication on Crossref: https://doi.org/10.1177/1098612x12473994