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Peer-reviewed veterinary case report

Hydrocortisone spray reduces itching and skin damage in dogs

By Nam, Eui-Hwa et al.·Published in Journal of veterinary science·2012·College of Veterinary Medicine and Research Institute for Veterinary Science, South Korea·View original on PubMed

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Original publication title: Evaluation of the effect of a 0.0584% hydrocortisone aceponate spray on clinical signs and skin barrier function in dogs with atopic dermatitis.

Species:
dog

Plain-English summary

A group of 21 dogs with atopic dermatitis (a skin allergy condition) were treated with a topical spray containing hydrocortisone aceponate for either 7 or 14 days. Owners noticed a significant reduction in skin lesions and itching after treatment, and the dogs' skin barrier function improved as well. The spray was applied once daily, and by the end of the treatment period, the dogs showed marked improvement in their symptoms. This suggests that hydrocortisone aceponate is an effective option for managing atopic dermatitis in dogs.

People also search for: dog skin allergy treatment · hydrocortisone spray for dogs · atopic dermatitis in dogs symptoms

Abstract

The purpose of this study was to evaluate the effects of a topical spray containing 0.0584% hydrocortisone aceponate (HCA) on canine atopic dermatitis (CAD) and to evaluate the skin barrier function during the treatment of CAD. Twenty-one dogs that fulfilled the diagnostic criteria for CAD were included in this study. The HCA spray was applied once a day to the lesions of all dogs for 7 or 14 days. Clinical assessment was performed before (day 0) and after treatment (day 14), and clinical responses were correlated with changes in skin barrier function. CAD severity significantly decreased after 14 days of HCA treatment based on the lesion scores (p < 0.0001), which were determined using the CAD extent and severity index (CADESI-03) and pruritus scores (p < 0.0001) calculated using a pruritus visual analog scale. Transepidermal water loss, a biomarker of skin barrier function, was significantly reduced compared to baseline (day 0) measurements (p = 0.0011). HCA spray was shown to be effective for significantly improving the condition of dogs suffering from CAD. This treatment also significantly improved cut.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/22705741/