Peer-reviewed veterinary case report
Does cannabidiol (CBD) help relieve osteoarthritis pain in dogs
By Mejia, Sebastian et al.·Published in Journal of the American Animal Hospital Association·2021·View original on PubMed →
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Original publication title: Evaluation of the Effect of Cannabidiol on Naturally Occurring Osteoarthritis-Associated Pain: A Pilot Study in Dogs.
- Species:
- dog
Plain-English summary
A group of 23 dogs with osteoarthritis (a type of joint pain) were given either a placebo or cannabidiol (CBD) to see if it would help relieve their pain. After six weeks of treatment, the researchers found no significant difference in pain relief or activity levels between the dogs receiving CBD and those on the placebo. Some dogs did experience side effects, including elevated liver enzymes and vomiting. Overall, CBD did not show clear benefits for managing osteoarthritis pain in these dogs.
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Abstract
The objective of this study was to provide preliminary data describing the safety and effect of cannabidiol (CBD) for symptom relief of canine osteoarthritis-associated pain in a clinical setting using objective outcome measures. Twenty-three client-owned dogs with naturally occurring osteoarthritis of appendicular joints completed this prospective, double-blinded, crossover, placebo-controlled study. Baseline data were acquired for 4 wk, followed by random allocation to either placebo or CBD treatment for 6 wk, followed by 6 wk with the opposite treatment. Outcome measures included objective gait analysis, activity counts (via accelerometry) and clinical metrology instruments. There were no differences noted between groups at any time point for any of the recorded outcome measures. Adverse events associated with CBD administration included elevation in liver enzymes (n = 14) and vomiting (n = 2).
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/33450016/