Peer-reviewed veterinary case report
Afoxolaner kills Haemaphysalis longicornis ticks on dogs within 48
By Kondo, Yumi et al.·Published in Veterinary parasitology·2014·Merial Japan Limited, Japan·View original on PubMed →
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Original publication title: Evaluation of the efficacy of afoxolaner against Haemaphysalis longicornis on dogs.
- Species:
- dog
Plain-English summary
A group of 16 beagle dogs were treated with a medication called afoxolaner to eliminate ticks, specifically the Haemaphysalis longicornis type. After just one dose, the dogs showed a complete elimination of existing ticks within 48 hours, and the treatment also provided strong protection against new tick infestations for at least 30 days. This means that afoxolaner is highly effective in keeping dogs tick-free after treatment.
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Abstract
A controlled study to assess the acaricidal efficacy of afoxolaner in dogs after a single oral administration was conducted against Haemaphysalis longicornis ticks. The study was characterized by a negative controlled randomized block design and included sixteen beagle dogs of both sexes. Starting two days before treatment, each dog was infested weekly with 50 ticks over 4 weeks. The number of live ticks was determined 48 h after treatment and then 48 h after each infestation. The mean dose of afoxolaner received by dogs was 3.0mg/kg (range: 2.5-3.1mg/kg). Afoxolaner rapidly eliminated pre-existing tick infestations (100% ticks killed within 48 h of treatment) and controlled weekly re-infestations (91.9% prophylactic efficacy at Day 30).
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/24629429/