Peer-reviewed veterinary case report
Afoxolaner kills two European tick species on dogs within 48 hours
By Dumont, Pascal et al.·Published in Veterinary parasitology·2014·Merial SAS, France·View original on PubMed →
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Original publication title: Evaluation of the efficacy of afoxolaner against two European dog tick species: Dermacentor reticulatus and Ixodes ricinus.
- Species:
- dog
Plain-English summary
A group of dogs, including beagles and mongrels, were tested for tick infestations caused by two common European tick species. They were given a new oral medication called afoxolaner to see how well it worked against the ticks. The treatment showed impressive results, eliminating over 99% of existing ticks and preventing new infestations for up to 30 days. This means that afoxolaner is very effective at keeping dogs tick-free when given as directed.
People also search for: dog tick prevention · afoxolaner for dogs · how to get rid of ticks on dogs
Abstract
The acaricidal efficacy of a novel oral formulation of afoxolaner (NEXGARD(®), Merial) against two European tick species was assessed in dogs experimentally infested with Ixodes ricinus and Dermacentor reticulatus. Three studies, each characterized by a negative controlled randomized block design, were conducted with a total of 52 beagle or mongrel dogs of both sexes. Starting 2 days before treatment, each dog was infested weekly with approximately 50 ticks. The number of live ticks was counted at 48 h post-treatment (Day 2) as well as 48 h following each infestation on Days 9, 16, 23, and 30. Afoxolaner, administered at an average dose of 2.7 mg/kg bodyweight (range 2.5-2.9 mg/kg), rapidly eliminated the pre-existing tick infestations with over 99% acaricidal efficacy and controlled the weekly re-infestations for up to 30 days post treatment with over 96% efficacy on both tick species. Afoxolaner provides excellent acaricidal efficacy against these two major European tick species using the oral route of administration.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/24629424/