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Peer-reviewed veterinary case report

Topical enilconazole treatment for fungal skin infection in Persian

By Hnilica, Keith A & Medleau, Linda·Published in Veterinary dermatology·2002·College of Veterinary Medicine, United States·View original on PubMed

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Original publication title: Evaluation of topically applied enilconazole for the treatment of dermatophytosis in a Persian cattery.

Species:
cat

Plain-English summary

A group of 22 Persian cats in a breeding cattery were treated for a persistent fungal skin infection caused by Microsporum canis. The cats received a topical antifungal called enilconazole, applied every three days for a total of eight treatments. Most cats showed improvement and tested negative for the fungus within 28 days. However, by 180 days, some cats had relapsed, showing signs of the infection again. Overall, enilconazole was well tolerated, though a few cats experienced mild side effects like drooling and muscle weakness.

People also search for: Persian cat skin infection treatment · enilconazole for cats · fungal infection in cats symptoms

Abstract

Many Persian catteries have long-standing dermatophyte infections and are particularly difficult to treat. Enilconazole is a topical antifungal agent that has demonstrated good efficacy in recent studies. Twenty-two Persian cats naturally infected with Microsporum canis in a breeding cattery were treated with topical 0.2% enilconazole and monitored for 180 days. The treatments were repeated every 3 days for a total of eight applications. All the cats improved clinically and became culture negative by day 28. By day 180, four cats had developed clinical dermatophytosis and all cats had positive fungal cultures. In this study, topical 0.2% enilconazole was generally well tolerated but may have caused hypersalivation, idiopathic muscle weakness and slightly elevated serum alanine aminotransferase (ALT) concentrations. This study suggests that enilconazole may be used safely with little risk to the young, aged and gravid animals.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/11896967/