Peer-reviewed veterinary case report
Zoledronate treatment for high calcium in four dogs
By Schenk, Ashley et al.·Published in Journal of the American Animal Hospital Association·2018·From the College of Veterinary Medicine·View original on PubMed →
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Original publication title: Evaluation of Zoledronate as Treatment for Hypercalcemia in Four Dogs.
- Species:
- dog
Plain-English summary
Four dogs with high calcium levels (hypercalcemia) were treated with a medication called zoledronate. High calcium can lead to serious health issues, including kidney failure, so it’s important to manage it. After receiving zoledronate, all the dogs showed a decrease in their calcium levels, indicating that the treatment was effective. While the dogs generally tolerated the treatment well, one dog experienced a local allergic reaction. Overall, zoledronate proved to be a successful option for treating hypercalcemia in dogs.
People also search for: dog high calcium treatment · zoledronate for dogs · dog kidney failure symptoms
Abstract
Hypercalcemia is a biochemical abnormality that, when left untreated, can lead to life-threatening complications including renal failure. Bisphosphonates are routinely used to treat hypercalcemia, but most literature on veterinary patients describes the use of pamidronate. This retrospective case series describes the use of zoledronate for treatment of hypercalcemia in four dogs. Information including signalment, clinical signs, treatment, and outcome was collected. All dogs showed a decrease in total and ionized calcium concentrations after treatment with zoledronate. All treatments of zoledronate administered were well tolerated, but a previously unreported local hypersensitivity reaction was observed in one dog. This report is the first to document the efficacy of zoledronate for treatment of hypercalcemia in dogs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/30272485/