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Peer-reviewed veterinary case report

Evidence-based medicine and stem cell therapy: how do we know such technologies are safe and efficacious?

Journal:
The Veterinary clinics of North America. Equine practice
Year:
2011
Authors:
Clegg, Peter D & Pinchbeck, Gina L
Affiliation:
Department of Musculoskeletal Biology · United Kingdom
Species:
horse

Plain-English summary

This article talks about how veterinarians can use the best available research to make informed decisions about treatments, specifically focusing on stem cell therapy for horses. It emphasizes the importance of finding and using high-quality evidence to ensure that these therapies are safe and effective. The authors discuss the current methods for gathering this evidence and suggest ways to improve future studies on stem cell treatments. Overall, the goal is to make sure that any new therapies are backed by solid research before being widely accepted in veterinary care.

Abstract

Evidence-based medicine (EBM) refers to the conscientious, explicit, and judicious use of current best evidence from research for the care of an individual patient. Central to the adoption of EBM is both producing and identifying the best possible evidence for a particular intervention or therapy. This article identifies and reviews the approaches to producing and identifying the best possible evidence that is necessary for the full acceptance of stem cell therapies in the horse and reviews the approaches that will allow future clinical studies in stem cell therapies to provide the best evidence for determining efficacy.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/21872765/