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Peer-reviewed veterinary case report

Evidence that in vitro susceptibility of CD3+ T lymphocytes to equine arteritis virus infection reflects genetic predisposition of naturally infected stallions to become carriers of the virus.

Journal:
Journal of virology
Year:
2012
Authors:
Go, Yun Young et al.
Affiliation:
Department of Veterinary Science · United States
Species:
horse

Abstract

We investigated the correlation between in vitro susceptibility of CD3(+) T lymphocytes to equine arteritis virus (EAV) infection and establishment of persistent infection among 14 stallions following natural infections. The data showed that carrier stallions with a CD3(+) T lymphocyte susceptibility phenotype to in vitro EAV infection may be at higher risk of becoming carriers than those that lack this phenotype (P = 0.0002).

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Original publication: https://pubmed.ncbi.nlm.nih.gov/22933293/