Peer-reviewed veterinary case report
Exacerbation of protracted-relapsing experimental allergic encephalomyelitis in DA rats by gluten-free diet.
- Journal:
- APMIS : acta pathologica, microbiologica, et immunologica Scandinavica
- Year:
- 2004
- Authors:
- Di Marco, Roberto et al.
- Affiliation:
- Department of Microbiological and Gynaecological Sciences · Italy
- Species:
- rodent
Abstract
The observation of neurological dysfunctions resembling multiple sclerosis (MS) seen clinically and/or by MRI in patients with celiac disease has focused attention on the possibility that cryptic gluten sensitivity may be involved in the pathogenesis of MS. Here we study the effects of a gluten-free diet on the course of protracted-relapsing EAE in DA rats, serving as a preclinical model of human MS. The data show not only that this nutritional approach failed to ameliorate development of the disease but rather that it exacerbated the course.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/15601316/