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Peer-reviewed veterinary case report

Dog with eye bulging caused by sterile skin inflammation

By Sharpe, Emily K et al.·Published in Veterinary ophthalmology·2018·Department of Clinical Sciences, United States·View original on PubMed

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Original publication title: Exophthalmos due to sterile neutrophilic dermatosis in a dog.

Species:
dog

Plain-English summary

An 8-year-old male Bichon Frise was brought to the vet because of swelling and bulging in his right eye, along with painful swelling around the eye and skin sores on his feet and tail. After tests, including imaging and biopsies, the vet found severe inflammation in the skin without any infection, diagnosing him with sterile neutrophilic dermatosis (a type of skin condition). The dog responded well to treatment with corticosteroids to reduce inflammation and later continued on oral cyclosporine for maintenance. He eventually achieved clinical remission and his symptoms improved significantly.

People also search for: dog eye swelling treatment · Bichon Frise skin problems · corticosteroids for dog inflammation

Abstract

An 8-year-old castrated male Bichon Frise was presented to the Kansas State University Veterinary Health Center for evaluation of unilateral right-sided exophthalmos, suspected secondary to a retrobulbar abscess. The dog had acutely developed right-sided periorbital swelling, exophthalmos with pain on retropulsion, as well as multiple cutaneous exudative plaques on the feet and tail base. On ophthalmic examination, the dog also exhibited mild left-sided exophthalmos with decreased, nonpainful retropulsion. Orbital ultrasound and CT were performed to evaluate the extent of bilateral orbital disease. Incisional biopsies were obtained from the affected right periorbital tissues and skin of the feet, and histopathology revealed severe neutrophilic inflammation of the dermis with no organisms detected. Histologic changes were consistent with sterile neutrophilic dermatosis. The dog achieved clinical remission following treatment with initial immunosuppressive doses of corticosteroids and subsequent long-term maintenance therapy using oral cyclosporine.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/28294507/