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Peer-reviewed veterinary case report

Exosome-mediated delivery of microRNAs by root-knot nematodes.

Year:
2026
Authors:
Maxwell MWH et al.
Affiliation:
Faculty of Biological Sciences · United Kingdom

Abstract

Plant-parasitic nematodes secrete molecules to manipulate their hosts, but little is known about their mode of delivery and packaging. Here, we describe microRNA-containing exosomes that are secreted by root-knot nematodes and systemically increase host susceptibility. By revealing a novel mode of nematode-plant communication, our findings outline a mechanism for the delivery of nematode patho-molecules, offering a new target for disrupting parasitism at the level of vesicle-mediated delivery.

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Original publication: https://europepmc.org/article/MED/41662279