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Peer-reviewed veterinary case report

Experimental autoimmune hearing loss.

Journal:
The Journal of clinical investigation
Year:
2004
Authors:
Billings, Peter
Affiliation:
University of California · United States

Abstract

Understanding of autoimmune sensorineural hearing loss (ASNHL) has been hindered by the inaccessibility of the inner ear to biopsy and the lack of workable animal models. A report in this issue of the JCI describes a mouse model of CD4(+) T cell-mediated ASNHL induced by immunization with peptides from the inner ear-specific proteins cochlin and beta-tectorin.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/15085190/