Peer-reviewed veterinary case report
Experimental murine model of disseminated infection by Saksenaea vasiformis: successful treatment with posaconazole.
- Journal:
- Medical mycology
- Year:
- 2012
- Authors:
- Salas, Valentina et al.
- Affiliation:
- Unitat de Microbiologia · Spain
Abstract
We have determined the in vitro activity of amphotericin B (AMB) and posaconazole (PSC) against Saksenaea vasiformis using broth microdilution and disk diffusion methods and determined the minimal fungicidal concentration (MFC). PSC was found to have the greatest in vitro activity in all cases and was the most efficacious in prolonging survival and reducing the fungal load in an immunocompetent murine model of disseminated infection caused by four strains of the fungus.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/22458251/