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Peer-reviewed veterinary case report

Experimental Mycoplasma hominis infection of the genital tract in BALB/c mice.

Journal:
Bulletin of experimental biology and medicine
Year:
2004
Authors:
Shkarupeta, M M et al.
Affiliation:
Institute of Physicochemical Medicine
Species:
rodent

Abstract

We studied the ability of laboratory and clinical strains of Mycoplasma hominis to colonize the genital tract mucosa in BALB/c mice. Colonization with mycoplasma occurred only in mice receiving estrogen. Mycoplasma hominis strains obtained after 3-fold passage through the vaginal mucosa in mice and administered intravaginally in a dose of 0.5 x 10(8) CFU/ml caused infection in 100% animals. Inflammation in the lower genital tract was reduced by the 8th week after infection.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/15085246/