Peer-reviewed veterinary case report
Experimental Oronasal Transmission of Chronic Wasting Disease Agent from White-Tailed Deer to Suffolk Sheep.
- Journal:
- Emerging infectious diseases
- Year:
- 2021
- Authors:
- Cassmann, Eric D et al.
Abstract
Chronic wasting disease (CWD) is a fatal prion disease of cervids. We examined host range of CWD by oronasally inoculating Suffolk sheep with brain homogenate from a CWD-positive white-tailed deer. Sixty months after inoculation, 1/7 sheep had immunoreactivity against the misfolded form of prion protein in lymphoid tissue. Results were confirmed by mouse bioassay.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/34808075/