Peer-reviewed veterinary case report
Expression of a beta-defensin mRNA, lingual antimicrobial peptide, in bovine mammary epithelial tissue is induced by mastitis.
- Journal:
- Infection and immunity
- Year:
- 2004
- Authors:
- Swanson, Kara et al.
- Affiliation:
- Dairy Biotechnology
Abstract
The expression of a beta-defensin, the lingual antimicrobial peptide (LAP), in response to mastitis was investigated by real-time PCR of RNA from mastitic and control udder quarters. There was a positive relationship between somatic cell count in milk and LAP expression. In situ hybridization showed that LAP mRNA was expressed in epithelial cells of mastitic tissue. These results suggest that LAP plays a role in the innate immune response to mastitis.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/15557657/