Peer-reviewed veterinary case report
Expression of interleukin-9 and its upstream stimulating factors in rats with ischemic stroke.
- Journal:
- Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
- Year:
- 2015
- Authors:
- Lin, Yinyao et al.
- Affiliation:
- Department of Neurology · China
- Species:
- rodent
Abstract
To investigate the temporal expressions of IL-9 and its related cytokines after middle cerebral artery occlusion in rats. IL-9 and its related cytokines in ischemia brain and blood were tested after rats were subjected to transient focal ischemia. Comparing with sham-operated group, the levels of IL-4, TGF-β, PU.1, IRF4, OX40, NIK, RelB-p52 and IL-9 in experimental groups were significantly higher after middle cerebral artery occlusion. The results showed that expressions of IL-9 and its upstream stimulating factors increased in experimental stroke, and whether they play a role or just a secondary change is awaiting further research.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/25652434/