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Peer-reviewed veterinary case report

Cat with extra-adrenal pheochromocytoma tumor causing heart arrhythmia

By Patnaik, A K et al.·Published in Journal of the American Veterinary Medical Association·1990·Department of Pathology, United States·View original on PubMed

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Original publication title: Extra-adrenal pheochromocytoma (paraganglioma) in a cat.

Species:
cat

Plain-English summary

An 18-year-old spayed domestic shorthair cat was found to have a tumor near her adrenal glands, which was causing temporary heart rhythm issues during surgery. The tumor was not visible on X-rays but could be felt during a physical exam. After careful removal, the tumor was confirmed to be producing hormones, which can affect heart function. The cat underwent surgery successfully, and while the details on her recovery weren't provided, the removal of the tumor is a crucial step in addressing her health concerns.

People also search for: cat heart problems · cat tumor surgery · why is my cat's heart racing · feline pheochromocytoma treatment

Abstract

Extra-adrenal pheochromocytoma (paraganglioma) arising from periadrenal tissue was diagnosed in an 18-year-old spayed domestic shorthair cat. The tumor was palpable on physical examination, but not apparent on plain radiographs. The cat developed temporary cardiac arrhythmia while the mass was being handled during excision, suggesting that the tumor was functional. The tumor was characterized histologically by nests and sheets of neoplastic cells separated by thin, vascular stroma. The cells had abundant eosinophilic granular cytoplasm and prominent nuclei. Diffuse, dark, intracytoplasmic granules were seen in sections stained with Grimelius stain. Ultrastructurally, the cells contained round and oblong, membrane-limited, dense core neurosecretory-type granules. Serotonin was detected in the cytoplasm of the neoplastic cells by use of immunocytochemical analysis.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/2370206/