Peer-reviewed veterinary case report
Mast cell tumors in dogs and cats - what to know
By Fischer, Britta M et al.·Published in Veterinary ophthalmology·2024·Department of Ophthalmology, Germany·View original on PubMed →
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Original publication title: Eyelid and conjunctival mast cell tumors: A retrospective study of 26 dogs and 8 cats.
- Species:
- dog
Plain-English summary
A 7-year-old Labrador and a 9-year-old cat were diagnosed with eyelid and conjunctival mast cell tumors, which are types of skin tumors. The tumors were surgically removed, and in cases where the surgery achieved clean margins, there were no recurrences. However, tumors located at the junction of mucous membranes and skin were found to be more aggressive and could spread to lymph nodes. Overall, most of the tumors were low-grade, meaning they were less likely to cause serious problems after removal.
People also search for: dog eyelid tumor treatment · cat conjunctival tumor symptoms · mast cell tumor surgery recovery
Abstract
OBJECTIVE: The objective of the study was to describe clinical and histologic characteristics of eyelid (LMCT) and conjunctival (CMCT) mast cell tumors in dogs and cats presented to a referral clinic in Germany. ANIMAL STUDIED: Medical records were reviewed to identify dogs and cats diagnosed with LMCTs or CMCTs between 2006 and 2020. RESULTS: LMCT were diagnosed in 31 patients and were cutaneous (n = 28; 20 dogs and 8 cats) or subcutaneous (three dogs). Five cases involved the mucocutaneous junction (four dogs, one cat). CMCTs occurred only in dogs (n = 3). At the time of presentation two of the four canine LMCT cases involving the mucocutaneous junction had metastasized to a mandibular lymph node. When applying the Kiupel system, both these cases were categorized as high grade. 85.7% (18/21) of the canine (19 cutaneous and 2 subcutaneous) LMCT and all CMCT cases were categorized as Kiupel low grade. No local recurrences occurred in all LMCT cases in which clean surgical margins were obtained (n = 18, mean surgical margin width: dogs 9.4 mm, cats 3.8 mm). Two cats (2/4) and four dogs (4/7) with questionable or incomplete surgical margins experienced local recurrences (mean time to recurrence of 180 and 637 days in dogs and cats, respectively). CONCLUSION: Recurrence of low-grade LMCTs and CMCTs following excision with clean margins is rare. Tumors involving the mucocutaneous junction may be of higher grade and prone to lymphatic metastasis.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/37902116/