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Peer-reviewed veterinary case report

Facial nerve tumor in a young cat with feline leukemia virus

By Paula Reis Pereira et al.·Published in Ciência Rural·View original on DOAJ

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Original publication title: Facial nerve ganglioneuroblastoma in a feline leukemia virus-positive cat

Species:
cat

Plain-English summary

An 11-month-old cat with feline leukemia virus was brought in showing signs like not eating well, a tilted head, and trouble moving its left lip. The veterinarian found a tumor affecting the facial nerve, which was confirmed through tests. Unfortunately, due to the severity of the condition and the cat's overall health, treatment options were limited. The diagnosis of a ganglioneuroblastoma (a type of nerve tumor) was made, but the cat's prognosis was poor.

People also search for: cat not eating · cat head tilt · feline leukemia virus treatment · cat facial nerve tumor · cat neurological symptoms

Abstract

ABSTRACT: Neuroblastic tumors can originate from the central neuraxis, olfactory epithelium, adrenal medullary region or autonomous system. Ganglioneuroblastoma are a type of neuroblastic tumor, with very few case descriptions in animals. Diagnosis of facial nerve ganglioneuroblastoma was made in a feline leukemia virus-positive 11-month-old cat. The cat had hyporexia, left head tilt, depressed mental state, horizontal nystagmus, inability to retract the pinched left lip, anisocoria, ptosis, and absence of the menace reflex. Gross necropsy showed a mass at the left facial nerve root region. Histological examination of this mass showed neoplastic proliferation of neuroblasts arranged in a cohesive pattern and mature ganglion cells. Ganglion cells were positive for neurofilament, neuron-specific enolase, S100, and glial fibrillary acidic protein by immunohistochemistry, while neuroblasts were positive for vimentin, S100, neuron-specific enolase and feline leukemia virus.

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Original publication on DOAJ: https://doi.org/10.1590/0103-8478cr20160675