Peer-reviewed veterinary case report
Dog with repeated intestinal bleeding linked to rare blood factor
By Otto, C M et al.·Published in Journal of the American Veterinary Medical Association·1991·Department of Small Animal Medicine, United States·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Factor XII and partial prekallikrein deficiencies in a dog with recurrent gastrointestinal hemorrhage.
- Species:
- dog
Plain-English summary
A 1-year-old Chinese Shar Pei was brought in for repeated episodes of bloody diarrhea and gastrointestinal bleeding. Tests showed the dog had low iron levels and low protein, indicating blood loss. Although a mild bowel disease was found during a necropsy, it didn't explain the severe bleeding. The dog was diagnosed with a rare condition called Factor XII deficiency, which might have contributed to the bleeding issues. Unfortunately, the exact cause of the recurrent gastrointestinal hemorrhage remains unclear.
People also search for: dog bloody diarrhea · Chinese Shar Pei gastrointestinal bleeding · Factor XII deficiency in dogs
Abstract
Factor XII deficiency and impaired prekallikrein activity were diagnosed in a 1-year-old Chinese Shar Pei. The dog experienced repeated episodes of intestinal hemorrhage and diarrhea. Laboratory findings were compatible with blood loss (iron deficiency anemia and hypoproteinemia). Necropsy findings suggested mild infiltrative bowel disease that could have been responsible for the dog's diarrhea, but no explanation for the severe recurrent gastrointestinal hemorrhage could be found. Factor XII deficiency is uncommon in the dog and is not associated with hemorrhagic tendencies. The factor XII deficiency in this case may have contributed to the gastrointestinal hemorrhage.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/1995570/