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Peer-reviewed veterinary case report

Factors affecting the diagnostic utility of canine and feline cytological samples.

Journal:
The Journal of small animal practice
Year:
2017
Authors:
Sapierzyński, R et al.
Affiliation:
Department of Pathology and Veterinary Diagnostics

Plain-English summary

This study looked at how certain factors can affect the usefulness of cytology, which is a quick and simple test used to examine cells from pets. Researchers analyzed 100 samples taken from dogs and cats by general veterinarians and then examined by a specialist. They found that having clear and well-prepared samples, as well as including detailed medical history in the accompanying paperwork, can help the specialist provide better advice. The results suggest that improving the quality of the samples and the information provided can lead to more helpful diagnostic outcomes.

Abstract

OBJECTIVES: Cytology is a quick, inexpensive, minimally invasive and widely available diagnostic method, but rigorous cooperation between clinical cytopathologist and physician is necessary to obtain clinically useful results. The aim of this study was to identify factors that affect clinical usefulness of a cytological result when the cellular material was collected by a general veterinary practitioner and examined by a clinical cytopathologist. MATERIALS AND METHODS: Analysis of 100 fine-needle aspirates performed by private veterinarians and examined by the clinical cytopathologist. Factors dependent on a general veterinary practitioner who performed the biopsy such as comprehensiveness of a cover letter, number of smears sent and macroscopic appearance of smears, were included in the analysis. Patient species and location of the lesion were also included. RESULTS: Only two factors turned out to favour a cytological diagnosis: good macroscopic appearance of smears and superficial location of the lesion. Nevertheless, inclusion of the medical history of a patient in a cover letter proved to help a clinical cytopathologist make clinically useful suggestions. CLINICAL SIGNIFICANCE: Preparation of good quality smears and provision of a comprehensive cover letter will increase the likelihood of obtaining clinically useful cytological reports.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/27861909/