Peer-reviewed veterinary case report
What affects rabies vaccine success in young cats
By Tasioudi, Konstantia E et al.Ā·Published in Comparative immunology, microbiology and infectious diseasesĀ·2024Ā·Department of Molecular DiagnosticsĀ·View original on PubMed ā
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Original publication title: Factors affecting the outcome of primary rabies vaccination in young cats.
- Species:
- cat
Plain-English summary
A group of young cats was tested for their response to rabies vaccination, and nearly all (94.2%) met the required antibody levels for protection. The study found that the time since their last vaccination was the most important factor in determining how well they responded. Cats that received two vaccinations tended to have better antibody levels, while age, sex, breed, and the type of vaccine did not seem to affect the outcome. Overall, it appears that young cats generally respond well to rabies vaccines, especially if they are vaccinated on schedule.
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Abstract
Limited data exist on the factors affecting feline rabies vaccination outcomes during primary immunization. This study aimed to assess if specific factors (signalment, vaccination count, vaccine brand, and time since last vaccination) correlated with meeting global antibody titer standards and absolute titers in young cats given monovalent inactivated rabies vaccines. Analyzing a dataset from cats tested before their first annual booster using the FAVN test, logistic and linear regression models were applied. Among 379 cats, 94.2 % achieved titers meeting or exceeding the standard threshold (≥0.5 IU/ml). Time since last vaccination proved to be the primary predictor of vaccination success. Cats receiving two vaccinations tended toward higher titers. Age, sex, breed, and vaccine type showed no impact on outcomes. The present study indicates that vaccination failure in young cats is uncommon, and that the time interval from the latest vaccination is the single most important predictor of successful rabies vaccination.
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Search related cases āOriginal publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/39116543/