Peer-reviewed veterinary case report
Factors linked to resistant Staph infections in dogs
By Weese, J Scott et al.·Published in Journal of the American Veterinary Medical Association·2012·Department of Pathobiology, Canada·View original on PubMed →
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Original publication title: Factors associated with methicillin-resistant versus methicillin-susceptible Staphylococcus pseudintermedius infection in dogs.
- Species:
- dog
Plain-English summary
A group of dogs with skin infections caused by Staphylococcus pseudintermedius were studied to see how methicillin-resistant strains (MRSP) compared to methicillin-susceptible strains (MSSP). The most common issue was pyoderma, a type of skin infection. It was found that dogs who had received antibiotics in the month before their infection were much more likely to have MRSP. However, both MRSP and MSSP infections had similar outcomes when treated properly, highlighting the importance of careful antibiotic use and timely diagnosis to manage these infections effectively.
People also search for: dog skin infection treatment · MRSP vs MSSP in dogs · antibiotic resistance in dogs · pyoderma in dogs treatment
Abstract
OBJECTIVE: To compare methicillin-resistant Staphylococcus pseudintermedius (MRSP) and methicillin-susceptible S pseudintermedius (MSSP) infections in dogs. DESIGN: Multicenter case-control study. ANIMALS: Dogs with MRSP infections were matched, by hospital, with 2 MSSP controls, with the infections occurring immediately before and after the case infection. PROCEDURES: Signalment, historical, clinical, treatment, and outcome data were documented. Conditional logistic regression was performed. A manual stepwise backward elimination procedure was used to build the multivariable model. RESULTS: 56 case and 112 control dogs were enrolled. Pyoderma was the most common infection type in both groups. In the final multivariable model, systemic administration of antimicrobials within 30 days prior to infection was significantly associated with an MRSP versus an MSSP infection (OR, 9.9; 95% confidence interval, 3.59 to 27.53). CONCLUSIONS AND CLINICAL RELEVANCE: The association of prior antimicrobial administration and MRSP infection indicated the potential impact of routine antimicrobial use in veterinary medicine on antimicrobial resistance and the need for prudent use of these important drugs. Mortality rate was not significantly different between MRSP and MSSP infections; the lack of a significant difference suggested that MRSP was inherently no more virulent than MSSP, provided the infection was properly diagnosed and appropriate treatment was started. Basic concepts such as prudent antimicrobial use and early diagnosis through timely submission of appropriate culture specimens therefore can be important measures to try to reduce the impact of this pathogen.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/22657928/