Peer-reviewed veterinary case report
What affects glaucoma starting in the other eye of dogs with one eye
By Donohue, Laura K et al.·Published in Veterinary ophthalmology·2026·Department of Clinical Sciences, United States·View original on PubMed →
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Original publication title: Factors Influencing the Incidence and Onset of Primary Angle-Closure Glaucoma in the Unaffected Eye of Dogs.
- Species:
- dog
Plain-English summary
A group of 117 dogs with primary angle-closure glaucoma (PACG) in one eye were studied to see how likely they were to develop glaucoma in the other eye. Within five years, about 71% of these dogs went on to develop glaucoma in the unaffected eye, with an average time of just over two years until this happened. The study found that certain breeds, like Cocker Spaniels and Basset Hounds, were more affected, and there was no significant difference in outcomes based on the type of preventive treatment given. Unfortunately, no specific treatment was found to be better than others for preventing glaucoma in the second eye.
People also search for: dog glaucoma treatment · Cocker Spaniel eye problems · preventing glaucoma in dogs
Abstract
OBJECTIVE: To determine factors that may affect the onset of glaucoma in the unaffected, contralateral eye of dogs with primary angle-closure glaucoma (PACG). ANIMAL STUDIED: One hundred and seventeen dogs unilaterally affected by PACG. PROCEDURES: Multicenter retrospective study. Patient factors, examination findings, prophylactic treatments, and treatment failure dates were recorded. Treatment failure was defined as glaucoma onset in the contralateral eye (IOP > 25 mmHg); death prior to a second diagnosis was treated as a competing risk. Cumulative incidence plots and Cox proportional hazard models were used to visualize and test for associations between baseline characteristics and time to treatment failure. RESULTS: Mean age at first diagnosis was 8.3 years and 69.2% were female. Within 5 years, 70.9% of dogs with unilateral PACG developed glaucoma in the contralateral eye. Median time to treatment failure was 2.15 years. The most common purebred dogs were the Cocker Spaniel, Basset Hound, and Shih Tzu. Dogs with an initial diagnosis in the left eye had a 1.8-fold increased risk of treatment failure of the right eye. Time to treatment failure was not different between dogs receiving prophylactic topical carbonic anhydrase inhibitors versus beta-blockers, nor in dogs receiving versus not receiving topical corticosteroids. CONCLUSIONS: No treatment regimen was found to be superior to another for PACG prophylaxis. Future prospective studies are warranted to investigate complementary glaucoma management strategies.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/40485308/