Peer-reviewed veterinary case report
Thoracic aortic aneurysm in young Leonberg dogs runs in families
By Chetboul, Valérie et al.·Published in Journal of the American Veterinary Medical Association·2003·Unité, France·View original on PubMed →
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Original publication title: Familial aortic aneurysm in Leonberg dogs.
- Species:
- dog
Plain-English summary
A 6-month-old male Leonberg dog was diagnosed with a thoracic aortic aneurysm, which is a bulging in the aorta that can be serious. The diagnosis was made using various imaging tests, and it was found that the dog had a twisted aorta and other affected blood vessels. Further examination showed damage to the aorta's structure, which is concerning. This condition was also found in the dog's father and one of his brothers, suggesting a genetic link. Unfortunately, this is the first known case of a familial aortic aneurysm in dogs, highlighting the need for awareness in this breed.
People also search for: Leonberg dog aortic aneurysm · puppy heart problems · genetic heart issues in dogs
Abstract
A thoracic aortic aneurysm was diagnosed in a 6-month-old male Leonberg dog by use of radiography, transthoracic and transesophageal echocardiography, and magnetic resonance imaging. The aneurysm was associated with a twisted ascending aorta and dilatation of several other thoracic arteries (pulmonary trunk, brachiocephalic trunk, and left subclavian artery). Histologic examination of the aorta revealed cystic medial necrosis, with disruption of the elastic network, collagen fibers, and the muscle glycoprotein fibrillin-1. The dam and sire of the dog and 8 littermates were examined by use of transthoracic echocardiography. The sire and 1 male littermate also had an aneurysm of the ascending aorta. To the authors' knowledge, this is the first report of familial aortic aneurysm in dogs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/14584747/