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Peer-reviewed veterinary case report

Fanconi syndrome in small dogs linked to chicken jerky treats

By Hooper, Ashley N & Roberts, Brian K·Published in Journal of the American Animal Hospital Association·2011·Emergency and Critical Care Medicine Department, United States·View original on PubMed

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Original publication title: Fanconi syndrome in four non-basenji dogs exposed to chicken jerky treats.

Species:
dog

Plain-English summary

Four small-breed dogs were brought to the vet with symptoms like lethargy, vomiting, diarrhea, and increased thirst and urination after eating chicken jerky treats daily. Tests ruled out other issues, and they were diagnosed with Fanconi syndrome, a condition affecting kidney function. The dogs received supportive care, including IV fluids and nutritional supplements. Three of the dogs fully recovered and no longer showed signs of kidney issues, but one dog continued to have kidney problems and was diagnosed with chronic kidney disease.

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Abstract

Four small-breed dogs were diagnosed with acquired Fanconi syndrome. All dogs ate varying amounts of chicken jerky treats. All dogs were examined for similar clinical signs that included, but were not limited to, lethargy, vomiting, anorexia, diarrhea, and altered thirst and urination. The quantity of chicken jerky consumed could not be determined; however, based on the histories obtained, the chicken jerky treats were a significant part of the diet and were consumed daily by all dogs. Extensive diagnostic testing eliminated other causes of the observed clinical signs, such as urinary tract infection and rickettsial disease. Glucosuria in the face of euglycemia or hypoglycemia, aminoaciduria, and metabolic acidosis confirmed the diagnosis of Fanconi syndrome. All dogs received supportive care, including IV fluids, antibiotics, gastroprotectants, and oral nutritional supplements. Three dogs exhibited complete resolution of glucosuria, proteinuria, and the associated azotemia; however, one dog remained azotemic, resulting in a diagnosis of chronic kidney disease.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/22058368/