Peer-reviewed veterinary case report
Fatal gas gangrene from type A infection in Siberian Husky dog
By Sprohnle-Barrera, Cleide H et al.·Published in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·2022·School of Veterinary Science, Australia·View original on PubMed →
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Original publication title: Fatal non-traumatic gas gangrene caused bytype A in a Siberian Husky dog.
- Species:
- dog
Plain-English summary
An 8-year-old male Siberian Husky was brought to the emergency clinic after suddenly collapsing and showing severe swelling in his front legs and chest area. Despite immediate treatment, tests revealed he had severe gas gangrene caused by a type of bacteria, leading to multi-organ failure. Unfortunately, the dog passed away during treatment. A postmortem examination confirmed the presence of harmful bacteria in his body, which are known to cause this serious condition.
People also search for: Siberian Husky collapse · dog gas gangrene symptoms · emergency treatment for dog swelling
Abstract
An 8-y-old, castrated male Siberian Husky dog was admitted to an emergency clinic with acute collapse and severe swelling of both forelimbs, ventral thorax, and axillary region. The clinical assessment, with laboratory tests and radiologic investigation, confirmed severe subcutaneous emphysema and multi-organ failure. The animal died while receiving emergency treatment. On postmortem examination,was isolated from the subcutaneous fluid and the effusion from the thoracic and abdominal cavities. Relevant histopathology findings included subcutaneous emphysema and multi-organ perivascular and intravascular, intralesional myriad 0.5-3-µm gram-positive rod bacteria, with no associated inflammation. Whole-genome sequencing and phylogenetic analysis identifiedtype A. Virulence genes detected included(alpha toxin),(v-toxin),(collagenase A),(hyaluronidase),,,(sialidases), and(perfringolysin). These virulence genes have previously been reported to act synergistically with alpha toxin inmediated gas gangrene.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/35179099/