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Peer-reviewed veterinary case report

Feline babesiosis in South Africa causing anemia and lethargy

By Penzhorn, Banie L et al.·Published in Annals of the New York Academy of Sciences·2004·Department of Veterinary Tropical Diseases and Companion Animal Clinical Studies·View original on PubMed

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Original publication title: Feline babesiosis in South Africa: a review.

Species:
cat

Plain-English summary

A domestic cat in South Africa was diagnosed with babesiosis, a tick-borne infection caused by the Babesia felis parasite. The owner noticed symptoms like lack of appetite and extreme tiredness. Upon examination, the cat showed signs of anemia and jaundice, and lab tests confirmed the infection. The veterinarian treated the cat with primaquine phosphate, which helped improve its condition, although the treatment may need to be repeated since it doesn't completely eliminate the infection.

People also search for: cat lethargy and loss of appetite · babesiosis in cats treatment · South Africa cat anemia symptoms

Abstract

Babesia felis, originally identified in wild cats in the Sudan, was subsequently found to cause clinical disease in domestic cats. Although babesiosis in domestic cats has been reported sporadically from various countries, as a significant disease it appears to be a distinctly South African phenomenon. Apart from an inland focus, feline babesiosis is reported regularly only from coastal regions. The infection is assumed to be tick-borne, but the vector has not been identified. Feline babesiosis tends to be an afebrile, chronic, low-grade disease. The most frequently reported complaints by owners are anorexia and lethargy. The main clinical findings are anemia, depression, and occasionally icterus. Concurrent infections (e.g., Mycoplasma haemofelis, FeLV, FIV) may contribute to the clinical picture. Laboratory findings commonly include regenerative anemia, elevation of alanine transaminase (but not alkaline phosphatase) and total bilirubin concentrations, and a variety of electrolyte disturbances. Secondary immune-mediated hemolytic anemia can be seen occasionally. Drugs effective against other Babesia species give variable and questionable results. The drug of choice is primaquine phosphate, which effects a clinical cure but does not sterilize the infection. Repeated or chronic therapy may be required.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15604490/