Peer-reviewed veterinary case report
Feline Cancers: Cat-aloging the Mutational Landscape.
- Journal:
- Cancer discovery
- Year:
- 2026
- Species:
- cat
Abstract
Targeted sequencing of nearly 500 paired tumor-normal cat tissue samples, representing 13 cancers, has uncovered strong similarities with the human oncogenome, including recurrently mutated TP53 as a driver of multiple tumor types. This is the first time the domestic feline oncogenome has been comprehensively characterized, and the human parallels support utilizing cats more frequently in comparative oncology.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/41774833/