Peer-reviewed veterinary case report
FIV-positive cat in Brazil treated for Cryptococcus gattii infection
By Nayara de Fátima Lazameth-Diniz et al.·Published in Case Reports in Veterinary Medicine·2025·Laboratório de Micologia, GB·View original on DOAJ →
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Original publication title: Feline Cryptococcosis due to Cryptococcus gattii VGII (Recently Renamed as C. deuterogattii) in an FIV-Positive Cat With Demodicosis From Manaus, Central Amazon, Brazil
- Species:
- cat
Plain-English summary
A 20-month-old male domestic shorthair cat from Brazil was brought in with a runny nose, skin lesions on his neck, and a lump between his shoulder blades. He was also infected with feline immunodeficiency virus (FIV) and had a skin condition called demodicosis. Tests confirmed he had a fungal infection caused by Cryptococcus gattii. The cat was treated with fluconazole, a medication for fungal infections, and a topical treatment, leading to complete recovery from all symptoms.
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Abstract
This case report documents the diagnosis and successful treatment of cryptococcosis caused by Cryptococcus gattii VGII in a 20-month-old male domestic shorthair cat from Manaus, Brazil, which was concurrently infected with feline immunodeficiency virus (FIV) and diagnosed with demodicosis. The cat presented with mucopurulent nasal discharge, cutaneous lesions on the neck, and a subcutaneous mass between the shoulder blades. Laboratory investigations, including fine-needle aspiration cytology, fungal culture, and PCR-RFLP genotyping, confirmed the presence of C. gattii VGII. The cat was treated with fluconazole (10 mg/kg/day) and topical fluralaner–moxidectin, resulting in complete clinical resolution of all lesions and associated symptoms. This report underscores the significance of considering cryptococcosis as a differential diagnosis in immunocompromised cats presenting with cutaneous or respiratory symptoms. Additionally, it highlights the importance of recognizing the Amazon region as an area of environmental prevalence of C. gattii VGII, reinforcing the need for awareness regarding its impact on animal health.
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Search related cases →Original publication on DOAJ: https://doi.org/10.1155/crve/8368783