Peer-reviewed veterinary case report
Black nail base nodule in cat caused by Exophiala fungus
By Maeda, Hirofumi et al.·Published in The Journal of veterinary medical science·2008·College of Bioresource Sciences, Japan·View original on PubMed →
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Original publication title: Feline digital phaeohyphomycosis due to Exophiala jeanselmei.
- Species:
- cat
Plain-English summary
An 8-year-old male Japanese domestic cat had a black nodule about the size of a marble at the base of his nail. After the nodule was removed and examined, it was found to be caused by a type of fungus called Exophiala jeanselmei, which can lead to skin infections. The cat likely needed antifungal treatment to help clear the infection. With proper care, the cat can recover from this condition.
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Abstract
The black nodule measuring 1 cm in diameter developed in the base of nail of an 8-year-old Japanese domestic male cat. Histological examination of the excised nodule revealed a granulomatous lesion extending from the epidermis to adjacent bone. The lesion was consisted of diffuse infiltration of macrophages with epithelioid cells and multinucleated giant cells. These macrophages contained a few to numerous yeast-like brown pigmented fungus cells with a spherical shape and dark thick wall. The PCR amplification with universal primers of the 28S ribosomal RNA gene yielded a 628-bp fragment and the direct sequence confirmed that the diagnosis of the lesion was phaeohyphomycosis caused by the pathogenic dematiaceous fungus, Exophiala jeanselmei.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19122414/