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Peer-reviewed veterinary case report

Feline gastrointestinal eosinophilic sclerosing fibroplasia

Journal:
Brazilian Journal of Veterinary Pathology
Year:
2022
Authors:
Nicolás Enríquez et al.
Affiliation:
Veterinary Internal Medicine and Pharmacology Research Group MIFARVET, Animal Sciences Faculty, University of Nariño, Pasto, Colombia · BR
Species:
cat

Plain-English summary

A female Persian cat was brought in for a check-up after losing weight and occasionally vomiting for three months. During the examination, the cat showed signs of being very tired and had a high white blood cell count, along with a mass found in her small intestine. A closer look at the tissue revealed a type of non-cancerous growth made up of dense connective tissue and a lot of certain immune cells called eosinophils, which are often involved in allergic reactions or inflammation. This condition, known as feline eosinophilic sclerosing fibroplasia, is being reported for the first time in Colombia.

Abstract

A female Persian cat arrives for clinical assessment with a 3-month history of weight loss and sporadic vomiting. The clinical and paraclinical findings were hypodynamia cachexia, leukocytosis and presence of a mass in duodenum. Histopathological evaluation revealed a non-neoplastic tumor proliferation, which was organized into dense, sclerotic-like connective tissue trabeculae that anastomosed, with cells of spindle-shaped morphology, elongated and rounded nuclei with prominent nucleoli and fine granular chromatin. These cells were intermingled with abundant eosinophils and in smaller proportion lymphocytes, macrophages, plasma cells, with transmural distribution. Masson’s trichrome differential staining trabeculae of collagen fibers. Based on the clinical and microscopic findings, the diagnosis of feline eosinophilic sclerosing fibroplasia is established, being this pathology’s first documented report in Colombia.

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Original publication: https://doi.org/10.24070/bjvp.1983-0246.v15i1p57-61