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Peer-reviewed veterinary case report

How long do cats live with asymptomatic heartworm infection

By Genchi, Claudio et al.·Published in Veterinary parasitology·2008·Department of Animal Pathology (DIPAV), Italy·View original on PubMed

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Original publication title: Feline heartworm (Dirofilaria immitis) infection: a statistical elaboration of the duration of the infection and life expectancy in asymptomatic cats.

Species:
cat

Plain-English summary

A group of asymptomatic cats with heartworm infection were monitored to see how long they lived and whether they could recover on their own. Out of 43 cats studied, 34 (about 79%) managed to self-cure, meaning they no longer tested positive for heartworm, while 9 cats died during the follow-up period. The cats that remained symptom-free had a good chance of recovery, with some taking up to 48 months to clear the infection. Interestingly, older cats had a higher risk of dying from heartworm-related issues, but overall, heartworm-infected cats lived longer than those with other serious health problems.

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Abstract

A study was conducted to assess the duration and the outcome (self-cure or death) of feline heartworm infection and the life expectancy of infected cats. To be included in the study, cats had to be positive for heartworm antibody (Ab) and heartworm antigen (Ag) and had to demonstrate the presence of worms by echocardiography. Self-cure was defined as (1) negative for heartworm Ag and (2) no further visualization of worms by echocardiography. Of the 1962 eligible cats, 364 (18.5%) were positive for heartworm Ag and 131 were positive for heartworm Ag and for echocardiography diagnosis (prevalence 6.7%). None of the cats was microfilaremic. Of 43 asymptomatic cats included into the follow-up study with owners' consent, 34 (79%) self-cured and nine (21%) died. Eleven (26%) cats remained asymptomatic and self cured within 21-48 months, 23 (53%) showed symptoms but self-cured within 18-49 months, 6 (14%) died within 8-41 months of follow-up and 3 (7%) suddenly died after 38-40 months, which was related to heartworm infection. The probability for death or sudden death increased significantly with age at diagnosis, but no difference was detected by gender, survival time after diagnosis, or the presence or absence of symptoms. The presence/absence of symptoms showed significant interaction with the age at diagnosis (i.e., symptomatic cats showed increasing duration of heartworm infection along with age at diagnosis compared to that for asymptomatic cats. Heartworm-infected cats survived significantly longer than heartworm-negative cats affected by hypertrophic cardiomyopathy, chronic renal failure, or neoplastic diseases.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18922638/