Peer-reviewed veterinary case report
Amyloid deposits in the pancreas linked to diabetes in cats
By Yano, B. L. et al.·Published in Veterinary Pathology·1981·Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Minnesota, St. Paul, Minn.·View original on Crossref →
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Original publication title: Feline Insular Amyloid: Association with Diabetes Mellitus
- Species:
- cat
Plain-English summary
A group of 31 domestic cats with diabetes was studied, and it was found that 20 of them had amyloid deposits in their pancreas, which is linked to their diabetes. This suggests that the presence of these amyloid deposits may be related to the development of diabetes in cats. While the exact cause of this relationship wasn't determined, it seems that issues with the pancreas may occur before diabetes develops. If your cat has diabetes, it's important to discuss these findings with your veterinarian to understand how they might affect your cat's health.
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Abstract
Of 31 domestic cats with diabetes mellitus, 20 (65%) had amyloid deposits in their pancreatic islets (i.e., insular amyloid). The incidence of insular amyloidosis (p = 0.34) was not significantly different between diabetic and age-matched, non-diabetic cats from our previous study. Diabetic cats, however, had a significantly higher mean percentage of islets with amyloid (p = <.005) and a significantly higher mean percentage of islets with abundant amyloid deposits (p = <005) than did non-diabetic cats. These results suggest that insular amyloidosis and diabetes are causally related and are not simply concurrent diseases associated with aging. Although the specific relationship of insular amyloidosis to the pathogenesis of diabetes mellitus was not determined, a functional islet cell abnormality probably precedes the diabetic state and the deposition of insular amyloid.
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Search related cases →Original publication on Crossref: https://doi.org/10.1177/030098588101800507