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Peer-reviewed veterinary case report

Cat with swollen mammary glands after contraceptive

By Paulo Fernando Cisneiros da Costa Reis et al.·Published in Ciência Animal Brasileira·2008

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Original publication title: FELINE MAMMARY HYPERPLASIA: THERAPEUTIC SUCCESS WITH THE USE OF THE AGLEPRISTONE HIPERPLASIA MAMÁRIA FELINA: SUCESSO TERAPÊUTICO COM O USO DO AGLEPRISTONE

Species:
cat

Plain-English summary

A 9-month-old female Siamese cat was brought in with swollen mammary glands after receiving a contraceptive injection. The vet diagnosed her with mammary hyperplasia, a condition often triggered by hormones. They treated her with aglepristone, a medication that blocks progesterone, giving her a dose every 24 hours for five days. By the third day, her glands were less swollen and softer, and after 23 days, the swelling completely went away. The cat was then spayed, and the treatment was deemed effective and safe.

People also search for: cat swollen mammary glands · Siamese cat hyperplasia treatment · aglepristone for cats

Abstract

The feline mammary hyperplasia corresponds to a dependent injury of natural or synthetic progesterone. Although it is a benign condition, the clinical presentation, many times, it is an emergency. Thus the use of immediate protocols becomes necessary, as the use of aglepristone, which corresponds to a progesterone-antagonist drug. The aim of the present study corresponded to the description a case of feline mammary hyperplasia, with therapy the base of aglepristone. A feline, female, nine months of age, it presented description of increase of mammary volume, after the administration of a dose of contraceptive (medroxyprogesterone acetate). In virtue of anamnesis and the physical examination the diagnosis of mammary hyperplasia was established and was opted to the use of aglepristone, in the posology of 10mg/kg, to each 24h, during five days, it route subcutaneous. All the mammary glands presented symmetrical hyperplasia, with firm-elastic consistency. From the third day of the administration, it was observed that the glands were with more elastic consistency and lesser volume. After 23 days of the first dose, it had complete regression of the tissue mammary and the animal was neutered. Aglepristone if disclosed as an efficient therapy and insurance. <br /><br />KEY WORDS: Aglepristone, feline, hyperplasia, mammary gland. A hiperplasia mamária felina corresponde a uma lesão dependente de substâncias progestacionais naturais ou sintéticas. Embora seja uma condição benigna, a apresentação clínica, muitas vezes, é emergencial. Assim, torna-se necessário o uso de protocolos imediatos, como o uso do aglepristone, um fármaco antiprogestágeno. O presente trabalho descreveu um caso de hiperplasia mamária felina, com terapia à base de aglepristone. Um felino, fêmea, siamês, nove meses de idade, apresentou histórico de aumento de volume mamário após administração de uma dose do contraceptivo acetato de medroxiprogesterona. De acordo com a anamnese e o exame físico, foi estabelecido o diagnóstico presuntivo de hiperplasia mamária e optou-se pelo uso do aglepristone na posologia de 10 mg/kg a cada 24 horas, durante cinco dias, via subcutânea. Todos os pares de glândulas mamárias apresentavam hiperplasia simétrica, com consistência firme-elástica. A partir do terceiro dia da administração, observou-se que as glândulas estavam flácidas, consistência mais elástica e menor volume. Transcorridos 23 dias da primeira dose, constatou-se regressão completa do tecido mamário, sendo a gata  submetida à ovariossalpingo-histerectomia. O aglepristone se revelou como uma opção de tratamento eficaz e segura. <br /><br />PALAVRAS-CHAVES: Aglepristone, felino, glândula mamária, hiperplasia,

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